Grup de Recerca en Farmacoteràpia, Genòmica i Exposòmica (PHAGEX)

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Publicacions més rellevants de l’equip en els darrers tres anys

Articles a revistes

- Arranz MJ, Rodriguez-Gonzalez A, Perez-Blanco J, Penadés R, Gutierrez B, Ibañez L, Arias B, Brunet M, Cervilla J, Salazar J, Catalan R. “A pharmacogenetic intervention for the improvement of the safety profile of antipsychotic treatments (https://doi.org/10.1038/s41398-019-0511-9)”. Translational Psychiatry, 9: ar177, 2019. DOI: https://doi.org/10.1038/s41398-019-0511-9

- Draganov M, Arranz MJ, Salazar J, de Diego-Adelino J, Gallego- Fabrega C, Jubero M, Carceller-Sindreu M, Portella MJ. “Association study of polymorphisms within inflammatory genes and methylation status in treatment response in major depression”. European Psychiatry, 60: 7-13, 2019. DOI: https://doi.org/10.1016/j.eurpsy.2019.05.003

- Demontis et al (PGC consortium ADHD working group), MJ Arranz. “Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder”. Nature Genetics, 51(1), 2019. DOI: https://doi.org/10.1038/s41588-018-0269-7

- Bipolar Disorders and Schizophrenia Working Group of the PGC. MJ Arranz. “Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes”. Cell, 173(7): 1705-1715, 2018. DOI: https://doi.org/10.1016/j.cell.2018.05.046

- Martin, Walters, Demontis et al. (PGC consortium). “A genetic investigation of sex bias in the prevalence of ADHD”. Biological Psychiatry, 83: 1044-1053, 2018. DOI: https://doi.org/10.1016/j.biopsych.2017.11.026

- Anttila V et al. (Brainstorm consortium). “Analysis of shared heritability in common disorders of the Brain”. Science, 360(6395), 2018. DOI: 10.1126/science.aap8757

- Brandler WM, Antaki D, Gujral M, Kleiber ML, Maile MS, Hong O, Chapman TR, Tan S, Tandon P, Pang T, Tang SC, Vaux KK, Yang Y, Harrington E, Juul S, Turner DJ, Kingsmore SF, Gleeson JG, Kakaradov B, Telenti A, Venter JC, Corominas R, Cormand B, Rueda I, Messer KS, Nievergelt CM, Arranz MJ, Courchesne E, Pierce E, Muotri AR, MIakoucheva L, Hervas A, Corsello C, Sebat J. “Paternally inherited noncoding structural variants contribute to autism”. Science, 360(6386): 327-330, 2018. DOI: https://doi.org/10.1101/102327

- Van Hulzen, KJE et al. (PGC consortium). “Genetic Overlap between ADHD and BPD: Evidence from genome-wide association study meta- analyses”. Biological Psychiatry, 82(9): 634-641, 2017. DOI: https://doi.org/10.1016/j.biopsych.2016.08.040

- Arqueros C, Salazar J, Arranz MJ, Sebio A, Mora J, Sullivan I, Tobeña M, Martin-Richard M, Barnadas A, Baiget M, Paez D. “SPARC gene variants predict clinical outcome in locally advanced and metastatic pancreatic cancer patients”. Medical Oncology, 34(8): article number 136, 2017. DOI: 10.1007/s12032-017-0993-3

- Perez de los Cobos J, Alcaraz S, Siñol N, Arranz MJ, Trujols J, Batlle F, Calafell F, Duran-Sindreu S, Salazar J. “Association between satisfaction with methadone and opioid receptor gene polymorphisms in heroin-dependent patients unresponsive to methadone maintenance treatment”. Journal of Clinical Psychopharmacology.37(3):378-380, 2017.

- Moya P, Salazar J, Arranz MJ, Diaz-Torne C, del Rio E, Casademont J, Corominas H, Baiget M. “Methotrexate pharmacokinetic genetic variants are associated with outcome in rheumatoid arthritis patients”. Pharmacogenomics, 17(1):11-25, 2016. DOI: 10.2217/pgs.15.150

- Martin-Blanco A, Ferrer M, Soler J, Arranz MJ, Vega D, Calvo N, Elices M, Sanchez-Mora C, Garcia-Martinez I, Salazar J, Carmona C, Bauza J, Prat M, Perez V, Pascual JC. “The role of Hypothalamus-Pituitary-Adrenal genes and childhood trauma in Borderline Personality Disorders”. European Archives of Psychiatry and Clinical Neuroscience, 266(4):307, 2016. DOI: 10.1007/s00406-015-0612-2

- Arranz MJ, Gallego C, Salazar J, Arias B. “Pharmacogenetic studies of drug response in Schizophrenia”. Expert Review of Precision Medicine and Drug Development, 1(1): 79-91, 2016.

- I Sullivan; P Riera; M Andrés; A Altés; M Majem; R Blanco; L Capdevila; A Barba; A Barnadas; J Salazar. “Prognostic effect of VEGF gene variants in metastatic non-small-cell lung cancer patients”. Angiogenesis. 2019 Aug;22(3):433-440. DOI: 10.1007/s10456-019-09668-y

- David Páez, María Tobeña, Julen Fernández Plana, Ana Sebio, Anna C Virgili, Lluís Cirera; Agustí Barnadas; Pau Riera; Ivana Sullivan; Juliana Salazar. “Pharmacogenetic clinical randomised phase II trial to evaluate the efficacy and safety of FOLFIRI with high-dose irinotecan (HD-FOLFIRI) in metastatic colorectal cancer patients according to their UGT1A 1 genotyp”. British journal of cancer. 120-2, pp 190-195. 01/2019.

- P Riera; J Salazar; A Virgili; M Tobeña; A Sebio; P Gallano; A Barnadas; D Páez. “Relevance of CYP3A4*20, UGT1A1*37 and UGT1A1*28 variants in irinotecan-induced severe toxicity”. Br J Clin Pharmacol. 2018 Jun;84(6):1389-1392. DOI: 10.1111/bcp.13574

- Pau Riera; María V Apellániz; Juliana Salazar. “Relevance of the CYP3A4*20 variant as a predictor of paclitaxel-induced neuropathy in the Spanish population”. Medicina clinica. 150-4, pp 163-164, 2018. DOI: 10.1016/j.medcli.2017.09.004

- Pau Riera; Anna C Virgili; Juliana Salazar; Ana Sebio; María Tobeña; Ivana Sullivan; David Páez. “Genetic variants in the VEGF pathway as prognostic factors in stages II and III colon càncer”. Pharmacogenomics J. 2018 Jul;18(4):556-564. DOI:10.1038/s41397-017-0009-x.

- I Sullivan; J Salazar; C Arqueros; M Andrés; A Sebio; M Majem; J Szafranska; E Martínez; D Páez; A López Pousa; M Baiget; A Barnadas. “KRAS genetic variant as a prognostic factor for recurrence in resectable non-small cell lung càncer”. Clin Transl Oncol. 2017 Jul;19(7):884-890. DOI: 10.1007/s12094-017-1620-7.

- Patricia Moya; Hèctor Corominas; Juliana Salazar; César Díaz Torné. “A step forward in methotrexate pharmacogenetics”. Reumatol Clin. 2017 Sep - Oct;13(5):305. DOI: 10.1016/j.reuma.2016.12.002

- Brink M, Schäffer B, Vienneau D, Pieren R, Foraster M, Eze IC, Rudzik F, Thiesse L, Cajochen C, Probst-Hensch N, Röösli M, Wunderli JM. “Self-Reported Sleep Disturbance from Road, Rail and Aircraft Noise: Exposure-Response Relationships and Effect Modifiers in the SiRENE Study”. Int J Environ Res Public Health. 2019; 16:21.

- Brink M, Schäffer B, Vienneau D, Foraster M, Pieren R, Eze IC, Cajochen C, Probst-Hensch N, Röösli M, Wunderli JM. “A survey on exposure-response relationships for road, rail, and aircraft noise annoyance: Differences between continuous and intermittent noise”. Environ Int. 2019; 125:277-290.

- Héritier H*, Vienneau D*, Foraster M, Eze IC, Schaffner E, Hoogh K de, Thiesse L, Rudzik F, Habermacher M, Köpfli M, Pieren R, Brink M, Cajochen C, Wunderli JM, Probst-Hensch N, Röösli M, for the SNC study. “A systematic analysis of mutual effects of transportation noise and air pollution exposure on myocardial infarction mortality: a nationwide cohort study in Switzerland”. Eur Heart J. 2019; 40(7):598-603

- Vienneau D, Héritier H, Foraster M, Eze IC, Schaffner E, Thiesse L, Rudzik F, Habermacher M, Köpfli M, Pieren R, Brink M, Cajochen C, Wunderli JM, Probst-Hensch N, Röösli M; SNC study group. “Façades, floors and maps - Influence of exposure measurement error on the association between transportation noise and myocardial infarction”. Environ Int. 2019: 123: 399-406.

- Cole-Hunter T, de Nazelle A, Donaire-Gonzalez D, Kubesch N, Carrasco-Turigas G, Matt F, Foraster M, Martínez T, Ambros A, Cirach M, Martinez D, Belmonte J, Nieuwenhuijsen M. “Estimated effects of air pollution and space-time-activity on cardiopulmonary outcomes in healthy adults: A repeated measures study”. Environ Int 2018;121:741–50.

- Foraster M, Eze IC, Vienneau D, Schaffner E, Jeong A, Héritier H, Rudzik F, Thiesse L, Pieren R, Brink M, Cajochen C, Wunderli J-M, Röösli M, Probst-Hensch N. “Long-term exposure to transportation noise and its association with adiposity markers and development of obesity”. Environment International 2018;121:879–89.

- Héritier H, Vienneau D, Foraster M, Eze IC, Schaffner E, Thiesse L, Ruzdik F, Habermacher M, Köpfli M, Pieren R, Schmidt-Trucksäss A, Brink M, Cajochen C, Wunderli JM, Probst-Hensch N, Röösli M. “Diurnal variability of transportation noise exposure and cardiovascular mortality: A nationwide cohort study from Switzerland”. International Journal of Hygiene and Environmental Health 2018;221:556–63.

- Kempen EV, Casas M, Pershagen G, Foraster M. “WHO Environmental Noise Guidelines for the European Region: A Systematic Review on Environmental Noise and Cardiovascular and Metabolic Effects: A Summary”. International Journal of Environmental Research and Public Health 2018;15:379.

- Locher B, Piquerez A, Habermacher M, Ragettli M, Roosli M, Brink M, Cajochen C, Vienneau D, Foraster M, Muller U, Wunderli JM. “Differences between Outdoor and Indoor Sound Levels for Open, Tilted, and Closed Windows”. International Journal of Environmental Research and Public Health 2018;15.

- Mueller N, Rojas-Rueda D, Khreis H, Cirach M, Milà C, Espinosa A, Foraster M, McEachan RRC, Kelly B, Wright J, Nieuwenhuijsen M. “Socioeconomic inequalities in urban and transport planning related exposures and mortality: A health impact assessment study for Bradford, UK”. Environment International 2018;121:931–41.

- Nieuwenhuijsen, MJ, Gascon, M, Martinez, D, Ponjoan, A, Blanch, J, Garcia-Gil, MDM, Ramos, R, Foraster, M, Mueller, N, Espinosa, A, Cirach, M, Khreis, H, Dadvand, P, Basagana, X. “Air Pollution, Noise, Blue Space, and Green Space and Premature Mortality in Barcelona: A Mega Cohort”. Int J Environ Res Public Health 2018;15.

- Rudzik F, Thiesse L, Pieren R, Wunderli JM, Brink M, Foraster M, Héritier H, Eze IC, Garbazza C, Vienneau D, Probst-Hensch N, Röösli M, Cajochen C. “Sleep spindle characteristics and arousability from nighttime transportation noise exposure in healthy young and older individuals”. Sleep 2018 (ePub).

- Thiesse L, Rudzik F, Spiegel K, Leproult R, Pieren R, Wunderli JM, Foraster M, Héritier H, Eze IC, Meyer M, Vienneau D, Brink M, Probst-Hensch N, Röösli M, Cajochen C. “Adverse impact of nocturnal transportation noise on glucose regulation in healthy young adults: Effect of different noise scenarios”. Environment International 2018; 121(Pt 1):1011-1023.

- Zare Sakhvidi MJ, Zare Sakhvidi F, Mehrparvar AH, Foraster M, Dadvand P. “Association between noise exposure and diabetes: A systematic review and meta-analysis”. Environmental Research 2018;166:647–57.

- Arbillaga-Etxarri A, Gimeno-Santos E, Barberan-Garcia A, Benet M, Borrell E, Dadvand P, Foraster M, Marín A, Monteagudo M, Rodriguez-Roisin R, Vall-Casas P, Vilaró J, Garcia-Aymerich J. “Socio-environmental correlates of physical activity in patients with chronic obstructive pulmonary disease (COPD)”. Thorax 2017;72:796–802.

- Eze IC, Foraster M, Schaffner E, Vienneau D, Héritier H, Rudzik F, Thiesse L, Pieren R, Imboden M, von Eckardstein A, Schindler C, Brink M, Cajochen C, Wunderli J-M, Röösli M, Probst-Hensch N. “Long-term exposure to transportation noise and air pollution in relation to incident diabetes in the SAPALDIA study”. Int J Epidemiol 2017.

- Eze IC, Imboden M, Foraster M, Schaffner E, Kumar A, Vienneau D, Héritier H, Rudzik F, Thiesse L, Pieren R, von Eckardstein A, Schindler C, Brink M, Wunderli J-M, Cajochen C, Röösli M, Probst-Hensch N. “Exposure to Night-Time Traffic Noise, Melatonin-Regulating Gene Variants and Change in Glycemia in Adults”. Int J Environ Res Public Health 2017b;14. DOI: doi:10.3390/ijerph14121492

- Foraster M, Eze IC, Schaffner E, Vienneau D, Héritier H, Endes S, Rudzik F, Thiesse L, Pieren R, Schindler C, Schmidt-Trucksäss A, Brink M, Cajochen C, Marc Wunderli J, Röösli M, Probst-Hensch N. “Exposure to Road, Railway, and Aircraft Noise and Arterial Stiffness in the SAPALDIA Study: Annual Average Noise Levels and Temporal Noise Characteristics”. Environ Health Perspect 2017;125:097004.

- Fuks KB, Weinmayr G, Basagaña X, Gruzieva O, Hampel R, Oftedal B, Sørensen M, Wolf K, Aamodt G, Aasvang GM, Aguilera I, Becker T, Beelen R, Brunekreef B, Caracciolo B, Cyrys J, Elosua R, Eriksen KT, Foraster M, et al. “Long-term exposure to ambient air pollution and traffic noise and incident hypertension in seven cohorts of the European study of cohorts for air pollution effects (ESCAPE)”. Eur Heart J 2017;38:983–90.

- Héritier H*, Vienneau D*, Foraster M, Eze IC, Schaffner E, Thiesse L, Rudzik F, Habermacher M, Köpfli M, Pieren R, Brink M, Cajochen C, Wunderli JM, Probst-Hensch N, Röösli M, Group for the S study. “Transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland”. Eur J Epidemiol 2017;32:307–15.

- Mueller N, Rojas-Rueda D, Basagaña X, Cirach M, Cole-Hunter T, Dadvand P, Donaire-Gonzalez D, Foraster M, Gascon M, Martinez D, Tonne C, Triguero-Mas M, Valentín A, Nieuwenhuijsen M. “Urban and Transport Planning Related Exposures and Mortality: A Health Impact Assessment for Cities”. Environ Health Perspect 2017a;125:89–96.

- Mueller N, Rojas-Rueda D, Basagaña X, Cirach M, Cole-Hunter T, Dadvand P, Donaire-Gonzalez D, Foraster M, Gascon M, Martinez D, Tonne C, Triguero-Mas M, Valentín A, Nieuwenhuijsen M. “Health impacts related to urban and transport planning: A burden of disease assessment”. Environ Int 2017b;107:243–57.

- Schlatter F, Piquerez A, Habermacher M, Ragettli MS, Röösli M, Brink M, Cajochen C, Probst-Hensch N, Foraster M, Wunderli J-M. “Validation of large scale noise exposure modelling by long-term measurements”. Noise Mapping 2017;4:75–86.

- Marta H. Hernandez, Conxita Mestres, Pilar Modamio, Jaume Junyent, Lluis Costa-Tutusaus, Cecilia F. Lastra, Eduardo L. Mariño. “Adverse drug events in patients with dementia and neuropsychiatric/behavioral, and psychological symptoms, a one-year prospective study”. International Journal of Environmental Research and Public Health. 2019. Mar 15;16(6). pii: E934. DOI: doi: 10.3390/ijerph16060934

- M.Hernández, C.Mestres, P.Modamio, J.Junyent, C.F.Lastra, E.Mariño. “A two-year retrospective study of comorbidities and drug use in psychogeriatric patients”. Latin American Journal Of Pharmacy. 2018.37 (2):368-372.

- M.Hernández, C.Mestres, J.Junyent, LL. Costa-Tutusaus, P.Modamio, C.F.Lastra, E.Mariño. “Effects of a multifaceted intervention in psychogeriatric patients: one-year prospective study”. European Journal of Hospital Pharmacy. Published Online First: 26 November 2018. DOI: 10.1136/ejhpharm-2018-001647

- C.Mestres, M.Hernandez, A.Agustí, L.Puerta, B.Llagostera, P.Amorós. “Development of a pharmaceutical care program in progressive stages in geriatric institutions. BMC Geriatrics. Dec 19;18(1):316.

- S.Pérez, M.Espina, M.J.Gomara, J.L.Fidalfo, M.A.Alsina, C.Mestres, J.Miñones Conde. “Study of the interaction of GB virus C/Hepatitis G virus fusion peptides belonging to the E2 protein with phospholipid Langmuir monolayers”. Colloids and Surfaces B-Biointerfaces.2017.

- Mestres, C. “Current situation on nutrient-drug interactions in health care practice”. Integrative Food, Nutrition and Metabolism. 2017. 4(4):1-3

- Mestres C, Agustí A, Hernandez M, Puerta L, Llagostera B. “Pharmacist Intervention Program at Different Levels of Geriatric Healthcare”. Pharmacy. 2017 May 19;5(2).

- Mestres C. “Role of Pharmacists in Improving Drug Treatments”. Gerontology & Geriatric Studies. 2017. 1 (1)

- Torres B, Rius P, Guayta R, Gascón P. “Cribado oportunista del pulso irregular para la detección de fibrilación auricular en farmacias comunitarias de Cataluña”. Pharmaceutical Care España 2019; 21(1):6-22.

- Toledo D, Soldevila N, Guayta-Escolies R, Lozano P, Rius P, Gascón P, Domínguez A. “Knowledge of and Attitudes to Influenza Vaccination among Community Pharmacists in Catalonia (Spain)”. 2013-2014 Season: A Cross Sectional Study”. Int J Environ Res Public Health. 2017.

- Santolaya M, Aldea M, Grau J, Estrada M, Barau M, Buron A, Francesc M, Castell A, Rodriguez C, Gascón P, Rius P, Guayta-Escolies R; PROCOLON research group. “Evaluating the appropriateness of a community pharmacy model for a colorectal cancer screening program in Catalonia (Spain)”. J Oncol Pharm Pract. 2017 Jan;23(1):26-32. DOI: 10.1177/1078155215616278.

- Guayta-Escolies R., Rius P., Gascón M. P. “Sistemas personalizados de dosificación de medicamentos: ¿recurso o actividad asistencial?”. Formació Mèdica Continuada. 2016;23(2):47-9.

Llibres i capítols de llibre

- Duran, M; Mestres, C; Nogués R. “Fundamentos de Farmacología para Fisioterapeutas. Editorial Médica Panamericana. ISBN: 9788498359411. 2017.

- Duran, M; Mestres, C; Nogués R. (capítol Marta Hernández). “Fundamentos de Farmacología para Fisioterapeutas”. 297-313. Editorial Médica Panamericana. ISBN: 9788498359411. 2017.

- Duran, M; Mestres, C; Nogués R.“Interactions and incompatibilities between Drugs and Vehicles Used in Oral Administration. Food Drug Interactions. Pharmacokinetics, Prevention and Potential Side Effects”. Nova Science. ISBN: 978-1-53613-552-7. 2018.